Miscellanea. Properties of spending function boundaries

DOI10.1093/BIOMET/86.2.466MaRDI QIDQ4267777zbMATH OpenOpenAlexFDO

Authors Michael A. Proschan

Publication date 31 January 2000

Published in Biometrika (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1093/biomet/86.2.466

zbMATH Keywords

clinical trial monitoringrepeated significance testing

Mathematics Subject Classification ID

Inference from stochastic processes (62M99) Applications of statistics to biology and medical sciences; meta analysis (62P10)

Recommendations

• Construction of a Continuous Stopping Boundary from an Alpha Spending Function
• Design and analysis of group sequential tests based on the type I error spending rate function
• Discrete Sequential Boundaries for Clinical Trials
• Group sequential designs using both type I and type II error probability spending functions
• Flexible Implementations of Group Sequential Stopping Rules Using Constrained Boundaries

Cited in

(4)

• On expenditure functions
• A generalization of the expenditure function
• Construction of a Continuous Stopping Boundary from an Alpha Spending Function
• Design and analysis of group sequential tests based on the type I error spending rate function

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