bi bi reaction ordered mechanism Michaelis Menten model with product 1 and single central complex (steady state assumption)

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deterministic model

dimensional model

mathematical model

nonlinear model

static model

Available identifiers

MaRDI QIDQ6675336

bi bi reaction with Single Central complex Michaelis Menten model following an ordered mechanism with product 1 formulated via the steady state assumption, named after Leonor Michaelis, Maud Menten

List of contained entities

Michaelis Menten equation (bi bi reaction ordered with product 1 and single central complex - steady state assumption)	$v_0=\frac{V_{max,f}{c}_{S_1}{c}_{S_2}}{K_{i{S}_1}{K}_{S_2}+K_{S_2}{c}_{S_1}+K_{S_1}{c}_{S_2}+\frac{K_{i{S}_1}{K}_{S_2}}{K_{i{P}_1}}{c}_{P_1}+c_{S_1}{c}_{S_2}+\frac{K_{S_1}}{K_{i{P}_1}}{c}_{S_2}{c}_{P_1}}$
	$K_{S_1}$ represents Michaelis constant substrate 1 (bi bi reaction ordered with single central complex - steady state assumption)
	$K_{S_2}$ represents Michaelis constant substrate 2 (bi bi reaction ordered with single central complex - steady state assumption)
	$K_{i{P}_1}$ represents inhibition constant
	$K_{i{S}_1}$ represents inhibition constant
	$V_{max,f}$ represents limiting reaction rate (bi bi reaction ordered mechanism with single central complex - forward)
	$c_{P_2}$ represents product concentration
	$c_{S_1}$ represents substrate concentration
	$c_{S_2}$ represents substrate concentration
	$v_0$ represents initial reaction rate
initial product 1 concentration (bi bi reaction ordered with product 1 - Michaelis Menten model)	$c_{P_1}(t=0)=c_{P_{1,0}}$	initial condition
	$c_{P_1}$ represents concentration
	$t$ represents time
initial product 2 concentration (bi bi reaction ordered without product 2 - Michaelis Menten model)	$c_{P_2}(t=0)=0$	initial condition
	$c_{P_2}$ represents concentration
	$t$ represents time
initial substrate 1 concentration (bi bi reaction ordered - Michaelis Menten model)	$c_{S_1}(t=0)=c_{S_{1,0}}$	initial condition
	$c_{S_1}$ represents concentration
	$t$ represents time
initial substrate 2 concentration (bi bi reaction ordered - Michaelis Menten model)	$c_{{\mathrm{S}}_2}(t=0)=c_{{\mathrm{S}}_{2,0}}$	initial condition
	$c_{{\mathrm{S}}_2}$ represents concentration
	$t$ represents time
law of mass action	$v=k\prod _{i=1}^n{c}_i$
	$c_i$ represents concentration
	$k$ represents reaction rate constant
	$n$ represents molecularity
	$v$ represents reaction rate
mass balance	${\delta }_t+\mathrm{\nabla }F=0$

List of computational tasks

nonlinear parameter estimation of enzyme kinetics

List of assumptions

steady state assumption

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