Andrews model

Community: MathModDB

deterministic model	dimensional model	mathematical model	nonlinear model	static model

Available identifiers

MaRDI QIDQ6775654

microbial growth model accounting for substrate inhibition, named after John F. Andrews

Also known as Haldane Model, Haldane-Andrews Model

Description

The Andrews model is a mathematical model that describes the specific growth rate of micoorganisms. It modifies the traditional Monod model to account for the negative effects of high substrate concentrations. When the substrate level becomes too high, the specific growth rate decreases due to inhibition. This model is widely used in fermentation and other bioprocesses to predict growth under inhibitory conditions.

List of contained entities

Andrews specific growth rate equation	$μ = \frac{μ_{m a x} c_{S}}{K_{M} + c_{S} + \frac{c_{S}^{2}}{K_{i}}}$
	$μ$ represents specific growth rate
	$μ_{m a x}$ represents maximum specific growth rate
	$c_{S}$ represents substrate concentration
	$K_{M}$ represents Monod constant
	$K_{i}$ represents inhibition constant (Andrews)

List of computational tasks

nonlinear parameter estimation (Andrews model)

Described at:

A mathematical model for the continuous culture of microorganisms utilizing inhibitory substrates	(invention)

Mathematical models specializing Andrews model

Monod equation	assumes	non-inhibiting substrate assumption

Further items linking to Andrews model

Item	Property
bacterial growth	modelled by

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