Model selection versus model averaging in dose finding studies

DOI10.1002/SIM.6991MaRDI QIDQ6946750zbMATH OpenFDO

Authors Kirsten Schorning, Björn Bornkamp, Frank Bretz, Holger Dette

Publication date 5 August 2025

Published in Statistics in Medicine (Search for Journal in Brave)

zbMATH Keywords

model selectionclinical trialssimulation studymodel averaging

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

Cites work

• scientific article; zbMATH DE number 720675 (Why is no real title available?)
• A new look at the statistical model identification
• Bagging predictors
• Bayesian model selection and model averaging
• Combining Multiple Comparisons and Modeling Techniques in Dose‐Response Studies
• Dose Finding – A Challenge in Statistics
• Dose finding in drug development.
• Estimating the dimension of a model
• Frequentist Model Average Estimators
• Model Selection and Model Averaging
• Model Selection: An Integral Part of Inference
• Model-based dose finding under model uncertainty using general parametric models
• Optimal Design of Experiments
• Regression and time series model selection in small samples
• Response-adaptive dose-finding under model uncertainty

Cited in

(4)

• Assessing the similarity of dose response and target doses in two non-overlapping subgroups
• Closed MCP-Mod for pairwise comparisons of several doses with a control
• Randomization-based inference for MCP-Mod
• Overcoming model uncertainty -- how equivalence tests can benefit from model averaging

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