Model structures and structural identifiability: what? why? how?

DOI10.1007/978-3-030-62497-2_10MaRDI QIDQ2058924zbMATH OpenOpenAlexFDO

Authors Jason M. Whyte

Publication date 10 December 2021

Full work available at URL https://arxiv.org/abs/2101.06382

Mathematics Subject Classification ID

General theory of mathematical modeling (00A71) General systems (93A10) System identification (93B30)

Abstract: We may attempt to encapsulate what we know about a physical system by a model structure, $S$. This collection of related models is defined by parametric relationships between system features; say observables (outputs), unobservable variables (states), and applied inputs. Each parameter vector in some parameter space is associated with a completely specified model in $S$. Before choosing a model in $S$ to predict system behaviour, we must estimate its parameters from system observations. Inconveniently, multiple models (associated with distinct parameter estimates) may approximate data equally well. Yet, if these equally valid alternatives produce dissimilar predictions of unobserved quantities, then we cannot confidently make predictions. Thus, our study may not yield any useful result. We may anticipate the non-uniqueness of parameter estimates ahead of data collection by testing $S$ for structural global identifiability (SGI). Here we will provide an overview of the importance of SGI, some essential theory and distinctions, and demonstrate these in testing some examples.

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Cites work

• A reconstruction and extension of Maple's assume facility via constraint contextual rewriting
• Equivalence and identifiability analysis of uncontrolled nonlinear dynamical systems.
• Generic controllability theorems for descriptor systems
• Global a priori identifiability of models of flow-cell optical biosensor experiments. (Abstract of thesis)
• scientific article; zbMATH DE number 193291 (Why is no real title available?)
• scientific article; zbMATH DE number 1941665 (Why is no real title available?)
• Identification of parametric models from experimental data. Transl. from an upd. French version by the authors, with the help of John Norton
• Minimal positive realizations: a survey of recent results and open problems.
• Numerical parameter identifiability and estimability: Integrating identifiability, estimability, and optimal sampling design
• On the gap between the structural controllability of time-varying and time-invariant systems
• Structural equivalence of linear systems and compartmental models
• Unidentifiable compartmental models: What to do?

Cited in

(5)

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