Modeling the Ames Salmonella/Microsome Assay

DOI10.2307/2532562MaRDI QIDQ4274334zbMATH OpenOpenAlexWikidataFDO

Authors Brian G. Leroux, Susana Bleuer, Louis H. Broekhoven, D. Krewski

Publication date 13 January 1994

Published in Biometrics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.2307/2532562

zbMATH Keywords

Ames Salmonella/microsome assaydiffusion of histidinegrowth of auxotrophic bacteriahistidine-independent prototrophic cellsquasi-likelihood methodreverse mutationstests for mutagenicity

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

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(3)

• Two stage model for carcinogenesis: Number and size distributions of premalignant clones in longitudinal studies
• Quantitative correlation of the \textit{in vitro} biological effect with parameters of molecular complexation in mutagen-interceptor systems
• Model-Based Statistical Procedures for the Analysis of in Vitro Mutagenesis Assays

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