Modular modelling of signalling pathways and their cross-talk

DOI10.1016/J.TCS.2012.07.003MaRDI QIDQ714863zbMATH OpenOpenAlexWikidataFDO

Authors Robin Donaldson, M. Calder

Publication date 11 October 2012

Published in Theoretical Computer Science (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.tcs.2012.07.003

zbMATH Keywords

modellingbiological modulessignalling networks

Mathematics Subject Classification ID

Systems biology, networks (92C42) Biomedical imaging and signal processing (92C55) Cell biology (92C37)

Recommendations

• Toward Modelling and Analysis of Transient and Sustained Behaviour of Signalling Pathways
• A declarative view of signaling pathways
• Rule-Based Modelling of Cellular Signalling
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• Probabilistic model checking of the PDGF signaling pathway

Cites work

• Combining Intra- and Inter-cellular Dynamics to Investigate Intestinal Homeostasis
• Feature interaction detection by pairwise analysis of LTL properties -- A case study
• Modeling and querying biomolecular interaction networks
• Process Algebra Modelling Styles for Biomolecular Processes
• Rule-Based Modelling of Cellular Signalling
• Some investigations concerning the CTMC and the ODE model derived from bio-PEPA

Cited in

(7)

• Modeling Protein Expression and Protein Signaling Pathways
• Toward Modelling and Analysis of Transient and Sustained Behaviour of Signalling Pathways
• A model and analysis of the AKAP scaffold
• Relating continuous and discrete PEPA models of signalling pathways
• A declarative view of signaling pathways
• A modular systems biological modelling framework studies cyclic nucleotide signaling in platelets
• Modelling and analysing neural networks using a hybrid process algebra

Describes a project that uses

Uses Software

• PRISM
• Bio-PEPA
• PEPA

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