Nested repeated confidence intervals in adaptive group sequential clinical trials

MaRDI QIDQ5190912zbMATH OpenFDO

Authors Joachim Hartung, Guido Knapp

Publication date 27 July 2009

zbMATH Keywords

acne papulopustulosaadaptive sample size planninggroup sequential trialstest of non-inferiority and superiority

Mathematics Subject Classification ID

Parametric tolerance and confidence regions (62F25) Sequential statistical analysis (62L10) Applications of statistics to biology and medical sciences; meta analysis (62P10)

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Cited in

(8)

• Corrected confidence intervals following a sequential adaptive clinical trial with binary responses
• Statistical inference in adaptive group sequential trials with the standardized mean difference as effect size
• Exact Confidence Bounds Following Adaptive Group Sequential Tests
• Adaptive designs for noninferiority trials
• Interim analyses using repeated confidence bands
• Improved repeated confidence bounds in trials with a maximal goal
• Repeated Confidence Intervals in Self‐Designing Clinical Trials and Switching between Noninferiority and Superiority
• Adaptive group sequential confidence intervals for the ratio of normal means

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