On a chemotaxis-hapotaxis model with nonlinear diffusion modelling multiple sclerosis

MaRDI QIDQ6442414zbMATH OpenFDO

Authors Simone Fagioli, Emanuela Radici, Licia Romagnoli

Publication date 3 July 2023

Mathematics Subject Classification ID

A priori estimates in context of PDEs (35B45) Reaction-diffusion equations (35K57) Degenerate parabolic equations (35K65) PDEs in connection with biology, chemistry and other natural sciences (35Q92) Cell movement (chemotaxis, etc.) (92C17)

Abstract: We investigated existence of global weak solutions for a system of chemotaxis-hapotaxis type with nonlinear degenerate diffusion, arising in modelling Multiple Sclerosis disease. The model consists of three equations describing the evolution of macrophages ($m$), cytokine ($c$) and apoptotic oligodendrocytes ($d$). The main novelty in our work is the presence of a nonlinear diffusivity $D(m)$, which results to be more appropriate from the modelling point of view. Under suitable assumptions and for sufficiently regular initial data, adapting the strategy in [30,44], we show the existence of global bounded solutions for the model analysed.

This page was built for publication: On a chemotaxis-hapotaxis model with nonlinear diffusion modelling multiple sclerosis

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q6442414)