One-sided tests in clinical trials with multiple endpoints

DOI10.1111/J.0006-341X.2001.01039.XMaRDI QIDQ3078858zbMATH OpenWikidataFDO

Authors Daniel Bloch, Tze Leung Lai, Pascale Tubert-Bitter

Publication date 1 March 2011

Published in Biometrics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1111/J.0006-341X.2001.01039.X

zbMATH Keywords

bootstrap testsefficacy and toxicityindifference zonemultivariate response

Mathematics Subject Classification ID

Testing in survival analysis and censored data (62N03) Applications of statistics to biology and medical sciences; meta analysis (62P10) Medical applications (general) (92C50)

Recommendations

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Cites work

• A multivariate analogue of the one-sided test
• An approximate likelihood ratio test for a normal mean vector with nonnegative components with application to clinical trials
• Exact t and F Tests for Analyzing Studies with Multiple Endpoints
• Group Sequential Tests for Bivariate Response: Interim Analyses of Clinical Trials with Both Efficacy and Safety Endpoints
• scientific article; zbMATH DE number 1104922 (Why is no real title available?)
• Monotone Discriminant Functions and Their Applications in Rheumatology
• On The Design and Analysis of Randomized Clinical Trials with Multiple Endpoints
• One-Sided Testing Problems in Multivariate Analysis
• Resampling methods for confidence intervals in group sequential trials
• Testing Hypotheses About an Identified Treatment When There are Multiple Endpoints
• The bootstrap and Edgeworth expansion
• The emperor's new tests. (With comments and a rejoinder).

Cited in

(14)

• On a multiple endpoints testing problem
• Some improved tests for multivariate one-sided hypotheses
• Combining global and marginal tests to compare two treatments on multiple endpoints
• A superiority-equivalence approach to one-sided tests on multiple endpoints in clinical trials
• A Note on One‐Sided Tests with Multiple Endpoints
• Testing Hypotheses About an Identified Treatment When There are Multiple Endpoints
• Directional Tests for the Analysis of Clinical Trials with Multiple Endpoints Allowing for Incomplete Data
• Assessing multiple endpoints with ordered alternatives
• Complementary hypotheses in safety surveillance
• Statistical tests based on new composite hypotheses in clinical trials reflecting the relative clinical importance of multiple endpoints quantitatively
• Adaptive Design and Estimation in Randomized Clinical Trials with Correlated Observations
• Approval policies for modifications to machine learning‐based software as a medical device: A study of bio‐creep
• Nonparametric directional testing for multivariate problems in conjunction with a closed testing principle
• Confirmatory adaptive designs for clinical trials with multiple time-to-event outcomes in multi-state Markov models

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