optbdmaeAT

Authors Dibaba Bayisa Gemechu, Legesse Kassa Debusho, Linda Haines

Last update 24 May 2025

Copyright license GNU General Public License, version 2.0

Software version identifier 1.0.1, PACKAGES.rds, 1.0.2

Description

Computes A-, MV-, D- and E-optimal or near-optimal block designs for two-colour cDNA microarray experiments using the linear fixed effects and mixed effects models where the interest is in a comparison of all possible elementary treatment contrasts. The algorithms used in this package are based on the treatment exchange and array exchange algorithms of Debusho, Gemechu and Haines (2018) <doi:10.1080/03610918.2018.1429617>. The package also provides an optional method of using the graphical user interface (GUI) R package tcltk to ensure that it is user friendly.

Cites work

Algorithmic construction of optimal block designs for two-colour cDNA microarray experiments using the linear mixed effects model

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