optconerrf

MaRDI QIDQ7371926CRANFDO

Authors Morten Dreher, Werner Brannath, Johanna zur Verth

Last update 3 September 2026

Copyright license GNU General Public License

Software version identifier PACKAGES.rds, 1.0.0, 1.0.1, 1.0.2, 1.0.3

Description

Design and analysis of confirmatory adaptive clinical trials using the optimal conditional error framework according to Brannath and Bauer (2004) <doi:10.1111/j.0006-341X.2004.00221.x>. An extension to the optimal conditional error function using interim estimates as described in Brannath and Dreher (2024) <doi:10.48550/arXiv.2402.00814> and functions to ensure that the resulting conditional error function is non-increasing are also available.

Cites work

• Optimal Conditional Error Functions for the Control of Conditional Power

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