P-value adjustment in sequential clinical trials

DOI10.1111/J.0006-341X.2002.01005.XMaRDI QIDQ3079060zbMATH OpenOpenAlexWikidataFDO

Authors Thomas D. Cook

Publication date 1 March 2011

Published in Biometrics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1111/j.0006-341x.2002.01005.x

zbMATH Keywords

group sequential clinical trialslikelihood principleP-value adjustment

Mathematics Subject Classification ID

Sequential statistical design (62L05) Applications of statistics to biology and medical sciences; meta analysis (62P10)

Recommendations

• Use of the randomization distribution in the analysis of sequential clinical trials
• A Note on repeated p-values for group sequential designs
• An overview of group sequential procedures
• Point and interval estimation following a sequential clinical trial
• Adaptive Sample Size Calculations in Group Sequential Trials

Cites work

• P-values for group sequential testing
• Discrete Sequential Boundaries for Clinical Trials
• Exact Confidence Intervals Following a Group Sequential Test
• Exact confidence intervals following a group sequential trial: A comparison of methods
• scientific article; zbMATH DE number 1348603 (Why is no real title available?)
• Sequential Trials, Sequential Analysis and the Likelihood Principle

Cited in

(4)

• On design and inference for two-stage adaptive clinical trials with dependent data
• A Note on repeated p-values for group sequential designs
• Use of the randomization distribution in the analysis of sequential clinical trials
• Utilities of the P-value distribution associated with effect size in clinical trials

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Uses Software

• R

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