Parameter estimation in systems of nonlinear equations

DOI10.1007/S002110050052MaRDI QIDQ1338828zbMATH OpenOpenAlexFDO

Authors Klaus Schittkowski

Publication date 21 November 1994

Published in Numerische Mathematik (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/s002110050052

zbMATH Keywords

least squares fitminimization of a sum of squares of nonlinear functionsnumerical resultsparameter estimation

Mathematics Subject Classification ID

Numerical mathematical programming methods (65K05) Nonlinear programming (90C30)

Review text

The model considered in the paper consists of a minimization of a sum of squares of nonlinear functions that depend on parameters to be estimated and on an independent model parameter. The system of nonlinear equations is solved to get model function values and the resulting data are then inserted into a standard parameter estimation code to compute the least squares fit. As an application the coupled mass equilibrium problem as the relationship between antibody and antigen determinant is described and numerical results based on laboratory data are included to test the algorithm.

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