Planning clinical trials to evaluate early detection programmes

DOI10.1093/BIOMET/84.4.817MaRDI QIDQ4376593zbMATH OpenOpenAlexFDO

Authors Ping Hu, Marvin Zelen

Publication date 1997

Published in Biometrika (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1093/biomet/84.4.817

zbMATH Keywords

Breast cancerClinical trialDesign of experimentsScreeningEarly detection

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

Recommendations

• Planning of randomized early detection trials
• Significance Tests for Cancer Screening Trials
• Modeling and optimization in early detection programs with a single exam
• Experimental design issues for the early detection of disease: novel designs
• Mortality Modeling of Early Detection Programs

Cited in

(13)

• The effect on survival of early detection of breast cancer in South Australia
• Identifiability of the joint distribution of age and tumor size at detection in the presence of screening
• Scheduling optimal examination times in a simple illness-death model
• Planning of randomized early detection trials
• Experimental design issues for the early detection of disease: novel designs
• Designing cancer screening trials for reduction in late-stage cancer incidence
• Approximate Bayesian computation for the natural history of breast cancer, with application to data from a Milan cohort study
• Modeling and optimization in early detection programs with a single exam
• Optimal schedules of cancer surveillance and tumor size at detection
• A Conditional Approach to Measure Mortality Reductions Due to Cancer Screening
• Multivariate distributions of clinical covariates at the time of cancer detection
• Instrumental variable estimation of early treatment effect in randomized screening trials
• Significance Tests for Cancer Screening Trials

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