Predictive Hierarchic Modeling of Operational Characteristics in Clinical Trials

DOI10.1080/03610918.2014.941488MaRDI QIDQ2816672zbMATH OpenOpenAlexFDO

Authors V. V. Anisimov

Publication date 25 August 2016

Published in Communications in Statistics. Simulation and Computation (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1080/03610918.2014.941488

zbMATH Keywords

clinical trialsanalytic modelingevolving processespatient enrollmentpredictive hierarchic modelingtrial operation

Mathematics Subject Classification ID

Medical applications (general) (92C50) Point processes (e.g., Poisson, Cox, Hawkes processes) (60G55) Special processes (60K99)

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Cites work

• Statistical Issues in Drug Development
• Statistical modeling of clinical trials (Recruitment and randomization)

Cited in

(7)

• Statistical modeling of clinical trials (Recruitment and randomization)
• Forecasting and optimizing patient enrolment in clinical trials under various restrictions
• A Bayesian approach for event predictions in clinical trials with time-to-event outcomes
• Performances of Poisson-gamma model for patients' recruitment in clinical trials when there are pauses in recruitment or when the number of centres is small
• Joint monitoring and prediction of accrual and event times in clinical trials
• Recruitment prediction for multicenter clinical trials based on a hierarchical Poisson–gamma model: Asymptotic analysis and improved intervals
• Additive cost modelling in clinical trial

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