Extension of the SAEM algorithm to left-censored data in nonlinear mixed-effects model: Application to HIV dynamics model

DOI10.1016/J.CSDA.2006.05.007zbMATH Open1157.62540OpenAlexW1997792006MaRDI QIDQ1010506FDOQ1010506

Authors: Adeline Samson, M. Lavielle, France Mentré 

Publication date: 6 April 2009

Published in: Computational Statistics and Data Analysis (Search for Journal in Brave)

Full work available at URL: https://www.hal.inserm.fr/inserm-00182360/file/samson_csda_hal.pdf

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zbMATH Keywords

SAEM algorithmMCMC algorithmHIV dynamicsaccept-reject algorithmnonlinear mixed-effects modelsleft-censored data

Mathematics Subject Classification ID

General nonlinear regression (62J02) Applications of statistics to biology and medical sciences; meta analysis (62P10) Stochastic approximation (62L20)

Cites Work

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• A Joint Model for Nonlinear Mixed-Effects Models With Censoring and Covariates Measured With Error, With Application to AIDS Studies
• Sampling-Based Approaches to Calculating Marginal Densities
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• Convergence of a stochastic approximation version of the EM algorithm
• Parameter expansion to accelerate EM: the PX-EM algorithm
• Maximum likelihood estimation in nonlinear mixed effects models
• Laplace's approximation for nonlinear mixed models
• Mixed Effects Models with Censored Data with Application to HIV RNA Levels
• Relationships between antiviral treatment effects and biphasic viral decay rates in modeling HIV dynamics
• Coupling a stochastic approximation version of EM with an MCMC procedure
• Exact and Approximate Inferences for Nonlinear Mixed-Effects Models With Missing Covariates
• A Comparison Study of Models and Fitting Procedures for Biphasic Viral Dynamics in HIV‐1 Infected Patients Treated with Antiviral Therapies
• Assessing antiviral potency of anti-HIV therapies in vivo by comparing viral decay rates in viral dynamic models
• Analysis of left-censored longitudinal data with application to viral load in HIV infection

Cited In (20)

• A new class of stochastic EM algorithms. Escaping local maxima and handling intractable sampling
• Flexible longitudinal linear mixed models for multiple censored responses data
• Maximum Likelihood Estimation of Long-Term HIV Dynamic Models and Antiviral Response
• Modeling the dynamics of biomarkers during primary HIV infection taking into account the uncertainty of infection date
• Censored mixed-effects models for irregularly observed repeated measures with applications to HIV viral loads
• Parameter estimation and treatment optimization in a stochastic model for immunotherapy of cancer
• Parameter estimation in a hierarchical random intercept model with censored response: an approach using a SEM algorithm and Gibbs sampling
• A refined parameter estimating approach for HIV dynamic model
• Heavy-tailed longitudinal regression models for censored data: a robust parametric approach
• On the curved exponential family in the Stochastic Approximation Expectation Maximization Algorithm
• Analysis of left-censored longitudinal data with application to viral load in HIV infection
• Joint modeling of the clinical progression and of the biomarkers' dynamics using a mechanistic model
• A flexible nonlinear mixed effects model for HIV viral load rebound after treatment interruption
• Phenomenological modeling of tumor diameter growth based on a mixed effects model
• Accurate estimation with one order statistic
• Investigate Data Dependency for Dynamic Gene Regulatory Network Identification through High-dimensional Differential Equation Approach
• A simple model for viral decay dynamics and the distribution of infected cell life spans in SHIV-infected infant rhesus macaques
• Design optimization in nonlinear mixed effects models using cost functions: application to a joint model of infliximab and methotrexate pharmacokinetics
• Estimating recurrent time using nonlinear mixed effects model in patients with colorectal cancer
• What controls the acute viral infection following yellow fever vaccination?

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