Detecting an interaction between treatment and a continuous covariate: a comparison of two approaches

DOI10.1016/j.csda.2006.12.041zbMath1161.62439OpenAlexW2011467140MaRDI QIDQ1020054

Karina Zapien, Patrick Royston, Willi Sauerbrei

Publication date: 29 May 2009

Published in: Computational Statistics and Data Analysis (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.csda.2006.12.041

zbMATH Keywords

bootstrapstabilityclinical trialsinteractionfractional polynomialstype 1 errorcontinuous covariates

Mathematics Subject Classification ID

Related Items (2)

Investigation of age–treatment interaction in the SPACE trial using different statistical approaches ⋮ A Simple Method for Estimating Interactions Between a Treatment and a Large Number of Covariates

Cites Work

• Responder identification in clinical trials with censored data
• Improving the robustness of fractional polynomial models by preliminary covariate transformation: a pragmatic approach
• Heuristics of instability and stabilization in model selection
• Patterns of treatment effects in subsets of patients in clinical trials

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