Krylov and steady-state techniques for the solution of the chemical master equation for the mitogen-activated protein kinase cascade

DOI10.1007/S11075-008-9239-YzbMATH Open1165.92019OpenAlexW2099263825MaRDI QIDQ1027792FDOQ1027792

Authors: S. MacNamara, Kevin Burrage 

Publication date: 30 June 2009

Published in: Numerical Algorithms (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s11075-008-9239-y

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zbMATH Keywords

stochastic simulationsKrylov subspace approximationstotal steady state approximations

Mathematics Subject Classification ID

Computational methods for stochastic equations (aspects of stochastic analysis) (60H35) Numerical solutions to stochastic differential and integral equations (65C30) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)

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Cited In (3)

• A study case for the analysis of asymptotic expansions beyond the tQSSA for inhibitory mechanisms in enzyme kinetics.
• New trends and perspectives in nonlinear intracellular dynamics: one century from Michaelis-Menten paper
• Uniform Asymptotic Expansions beyond the tQSSA for the Goldbeter--Koshland Switch

Uses Software

• Expokit

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