Interpreting CFSE obtained division histories of B cells in vitro with Smith-Martin and cyton type models

DOI10.1007/s11538-009-9418-6zbMath1173.92011WikidataQ33711336 ScholiaQ33711336MaRDI QIDQ1034926

Tim Mosmann, Alan S. Perelson, Edwin Hawkins, Ha Youn Lee, Hulin Wu, Martin S. Zand, Philip D. Hodgkin

Publication date: 9 November 2009

Published in: Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s11538-009-9418-6

zbMATH Keywords

CFSE; cyton model; B cell; IL-4; Smith-Martin cell cycle model; thymidine labeling

Mathematics Subject Classification ID

60G35: Signal detection and filtering (aspects of stochastic processes)

92C37: Cell biology

34K60: Qualitative investigation and simulation of models involving functional-differential equations

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Cites Work

• Estimating lymphocyte division and death rates from CFSE data
• Bootstrap methods for standard errors, confidence intervals, and other measures of statistical accuracy
• Modeling T cell proliferation and death in vitro based on labeling data: generalizations of the Smith-Martin cell cycle model
• Estimating division and death rates from CFSE data