Dynamics of the Scatchard model for ligand-receptor binding

DOI10.1016/0025-5564(88)90101-0MaRDI QIDQ1102225zbMATH OpenOpenAlexFDO

Authors Krzysztof Kowalski

Publication date 1988

Published in Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/0025-5564(88)90101-0

zbMATH Keywords

generalized method of Lyapunov functionsglobally asymptotically stableligand receptor bindingScatchard modelunique equilibrium

Mathematics Subject Classification ID

Stability of solutions to ordinary differential equations (34D20) Biophysics (92C05) Physiological, cellular and medical topics (92Cxx)

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(12)

• Ring formation in divalent-receptor-divalent-ligand interaction: Pseudocooperative shapes of Scatchard plots
• Interpretation of Scatchard plots for aggregating receptor systems
• Dynamics of the Adair model for ligand-receptor binding
• Simulation modeling of ligand receptor interactions at non-equilibrium conditions: Processing of noisy inputs by ionotropic receptors.
• Maximum likelihood estimation of the kinetics of receptor-mediated adhesion
• A model of cooperativity based on restricted binding: kinetic and thermodynamic analysis
• Derangement model of ligand-receptor binding
• Steady-states of receptor-ligand dynamics: a theoretical framework
• Fluctuations in the mass-action model for ligand-receptor binding
• Allostery in oligomeric receptor models
• Variational implicit-solvent predictions of the dry–wet transition pathways for ligand–receptor binding and unbinding kinetics
• On the numerical solution of the general ``ligand-gated neuroreceptors model via CAS Mathematica

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