Parameter-dependent transitions and the optimal control of dynamical diseases

DOI10.1007/BF02458882zbMath0652.92004OpenAlexW1992257689WikidataQ52579750 ScholiaQ52579750MaRDI QIDQ1107462

R. A. Latta, Paul E. Rapp, Alistair I. Mees

Publication date: 1988

Published in: Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/bf02458882

zbMATH Keywords

constrained optimizationLyapunov exponentscorrelation dimensionHurwitz polynomialsFletcher-Powell algorithmbifurcations to periodic solutionsBox algorithmcomputational search for parameter-dependent transitions of attractor topologyFiacco-McCormick algorithmFloquet coefficientsminimizing Hurwitz coefficientsoptimal responses to dynamical diseasesperiodic synthesis of cyclic AMP in DictyosteliumRosenbrock algorithmthree-dimensional nonlinear ordinary differential equation

Mathematics Subject Classification ID

Numerical optimization and variational techniques (65K10) Nonlinear systems in control theory (93C10) Medical applications (general) (92C50) Control/observation systems governed by ordinary differential equations (93C15) Methods of reduced gradient type (90C52) Physiological, cellular and medical topics (92Cxx)

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Uses Software

• DIFSUB

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