Parameter estimation in a two-compartment population pharmacokinetic model with destructive sampling

DOI10.1016/0025-5564(88)90012-0MaRDI QIDQ1108955zbMATH OpenOpenAlexFDO

Authors Richard D. McArthur

Publication date 1988

Published in Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/0025-5564(88)90012-0

zbMATH Keywords

two-compartment modelpharmacokineticsmeanscovariance structurestochastic modeldeterministic modelvariancesdestructive samplingparameter estimation methods

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Computational methods for problems pertaining to biology (92-08) Physiological, cellular and medical topics (92Cxx)

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Cites work

• scientific article; zbMATH DE number 194949 (Why is no real title available?)
• scientific article; zbMATH DE number 3271181 (Why is no real title available?)
• A Simplex Method for Function Minimization
• Analysis and identification of stochastic compartment models in pharmacokinetics: Implication for cancer chemotherapy
• Least Squares Estimation when the Covariance Matrix and Parameter Vector are Functionally Related
• Pharmacokinetics with uncertainties in rate constants. III: The inverse problem
• Stochastic Models of Compartmental Systems

Cited in

(7)

• A Population Pharmacokinetic Model with Time-Dependent Covariates Measured with Errors
• scientific article; zbMATH DE number 4074858 (Why is no real title available?)
• Statistical inference for two-compartment model parameters with bootstrap method and genetic algorithm
• scientific article; zbMATH DE number 794374 (Why is no real title available?)
• Recycled estimation of population pharmacokinetics models
• Parameter estimation using aggregate data
• Identification of pharmacokinetics models in the presence of timing noise

Describes a project that uses

Uses Software

• IMSL Numerical Libraries

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