Testing Multispecies Coalescent Simulators using Summary Statistics
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Publication:117403
DOI10.48550/ARXIV.1908.01424arXiv1908.01424MaRDI QIDQ117403FDOQ117403
Authors: Elizabeth Allman, Hector Baños, John Rhodes
Publication date: 4 August 2019
Abstract: As genomic scale datasets motivate research on species tree inference, simulators of the multispecies coalescent (MSC) process are essential for the testing and evaluation of new inference methods. However, the simulators themselves must be tested to ensure they give valid samples from the coalescent process. In this work we develop several statistical tools using summary statistics to evaluate the fit of a simulated gene tree sample to the MSC model. Using these tests on samples from four published simulators, we uncover flaws in several. The tests are implemented as an R package, so that both developers and users will be able to easily check proper performance of future simulators.
Applications of statistics to biology and medical sciences; meta analysis (62P10) Problems related to evolution (92D15)
Cited In (1)
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