Abstract: We propose a coefficient of conditional dependence between two random variables and given a set of other variables , based on an i.i.d. sample. The coefficient has a long list of desirable properties, the most important of which is that under absolutely no distributional assumptions, it converges to a limit in , where the limit is if and only if and are conditionally independent given , and is if and only if is equal to a measurable function of given . Moreover, it has a natural interpretation as a nonlinear generalization of the familiar partial statistic for measuring conditional dependence by regression. Using this statistic, we devise a new variable selection algorithm, called Feature Ordering by Conditional Independence (FOCI), which is model-free, has no tuning parameters, and is provably consistent under sparsity assumptions. A number of applications to synthetic and real datasets are worked out.
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