Multiscale Bayesian Survival Analysis

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Publication:128917

DOI10.1214/21-AOS2097zbMATH Open1486.62132arXiv2005.02889MaRDI QIDQ128917FDOQ128917

Ismaël Castillo, Stéphanie van der Pas, Stéphanie van der Pas, Ismaël Castillo

Publication date: 6 May 2020

Published in: The Annals of Statistics (Search for Journal in Brave)

Abstract: We consider Bayesian nonparametric inference in the right-censoring survival model, where modeling is made at the level of the hazard rate. We derive posterior limiting distributions for linear functionals of the hazard, and then for `many' functionals simultaneously in appropriate multiscale spaces. As an application, we derive Bernstein-von Mises theorems for the cumulative hazard and survival functions, which lead to asymptotically efficient confidence bands for these quantities. Further, we show optimal posterior contraction rates for the hazard in terms of the supremum norm. In medical studies, a popular approach is to model hazards a priori as random histograms with possibly dependent heights. This and more general classes of arbitrarily smooth prior distributions are considered as applications of our theory. A sampler is provided for possibly dependent histogram posteriors. Its finite sample properties are investigated on both simulated and real data experiments.


Full work available at URL: https://arxiv.org/abs/2005.02889





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