Stochastic models of telomere shortening

DOI10.1016/S0025-5564(98)10092-5zbMATH Open0943.92015OpenAlexW2120502657WikidataQ52217465 ScholiaQ52217465MaRDI QIDQ1307682FDOQ1307682

Authors: Peter Olofsson, Marek Kimmel 

Publication date: 10 September 2000

Published in: Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/s0025-5564(98)10092-5

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zbMATH Keywords

asymptotic behaviorcell agingreducible multitype branching processtelomeres

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Applications of branching processes (60J85)

Cites Work

• General branching processes as Markov fields
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• A branching process model of telomere shortening

Cited In (21)

• Stochastic modeling of length-dependent telomere shortening in \textit{Corvus monedula}
• A mathematical model of cellular apoptosis and senescence through the dynamics of telomere loss
• Mathematical modelling of telomere length dynamics
• Stationary distribution of telomere lengths in cells with telomere length maintenance and its parametric inference
• Dynamical equation of chromosome telomere in cellular automata
• An in silico investigation into the causes of telomere length heterogeneity and its implications for the Hayflick limit
• Do cells sense time by number of divisions?
• A Markovian growth dynamics on rooted binary trees evolving according to the Gompertz curve
• The Aldous-Shields model revisited with application to cellular ageing
• Stochastic simulations of normal aging and Werner's syndrome
• Examining a scaled dynamical system of telomere shortening
• Can telomere shortening explain sigmoidal growth curves?
• Stochastic modelling of the loss of telomeric sequences in cells with multiple chromosomes
• A kinetic model of telomere shortening in infants and adults
• Stabilization of telomeres in nonlinear models of proliferating cell lines
• Qualitative analysis of a PDE model of telomere loss in a proliferating cell population in the light of suns and stars
• Aging and immortality in a cell proliferation model
• Modelling the regulation of telomere length: the effects of telomerase and G-quadruplex stabilising drugs
• Modeling growth and telomere dynamics in \textit{Saccharomyces cerevisiae}
• Mathematical model and computer simulations of telomere loss
• Mathematical modeling of telomere shortening: an overview

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