Sequential estimation for two-stage and three-stage clinical trials

DOI10.1016/0378-3758(94)00033-6zbMath0803.62074OpenAlexW2132302888WikidataQ127492026 ScholiaQ127492026MaRDI QIDQ1338388

D. Stephen Coad

Publication date: 5 January 1995

Published in: Journal of Statistical Planning and Inference (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/0378-3758(94)00033-6

zbMATH Keywords

variancebiasclinical trialunknown meanslinear time trendcommon known varianceconditional normal distributionestimated treatment differencerandomised stagethree-stage trialtwo-stage trial

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Sequential statistical design (62L05) Sequential estimation (62L12)

Related Items (4)

A multi-treatment two stage adaptive allocation for survival outcomes ⋮ A Bayesian adaptive design for two-stage clinical trials with survival data ⋮ A two-stage adaptive allocation design for survival outcome with informative censoring ⋮ ESTIMATION FOLLOWING EXTENSION OF A STUDY ON THE BASIS OF CONDITIONAL POWER

Cites Work

• Some results on estimation for two—stage clinical trials
• On the bias of maximum likelihood estimation following a sequential test

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