Pharmacokinetic model of intravitreal drug injection

DOI10.1016/0025-5564(94)90018-3MaRDI QIDQ1340475zbMATH OpenOpenAlexWikidataFDO

Authors Kakuji J. Tojo, Akira Ohtori

Publication date 19 December 1994

Published in Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/0025-5564(94)90018-3

zbMATH Keywords

metabolismconcentration distributionlensintravitreal injectionciliary bodyelimination pathwayselimination profile of lomefloxacinposterior chamberretina- choroid-sclera membrane

Mathematics Subject Classification ID

Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)

Recommendations

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Cites work

• Membrane-moderated controlled release

Cited in

(6)

• Mathematical assessment of drug build-up in the posterior eye following transscleral delivery
• Mathematical model for degradation and drug release from an intravitreal biodegradable implant
• Drug delivery from ophthalmic lenses
• Computational modeling of intravitreal drug delivery in the vitreous chamber with different vitreous substitutes
• Virtual pharmacokinetic model of human eye
• Computational modeling of drug distribution in the posterior segment of the eye: effects of device variables and positions

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