Pharmacokinetic model of intravitreal drug injection

DOI10.1016/0025-5564(94)90018-3zbMATH Open0805.92013OpenAlexW1988057984WikidataQ52371919 ScholiaQ52371919MaRDI QIDQ1340475FDOQ1340475

Authors: Kakuji J. Tojo, Akira Ohtori 

Publication date: 19 December 1994

Published in: Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/0025-5564(94)90018-3

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zbMATH Keywords

metabolismconcentration distributionlensintravitreal injectionciliary bodyelimination pathwayselimination profile of lomefloxacinposterior chamberretina- choroid-sclera membrane

Mathematics Subject Classification ID

Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)

Cites Work

• Membrane-moderated controlled release

Cited In (6)

• Mathematical assessment of drug build-up in the posterior eye following transscleral delivery
• Virtual pharmacokinetic model of human eye
• Computational modeling of drug distribution in the posterior segment of the eye: effects of device variables and positions
• Computational modeling of intravitreal drug delivery in the vitreous chamber with different vitreous substitutes
• Mathematical model for degradation and drug release from an intravitreal biodegradable implant
• Drug delivery from ophthalmic lenses

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