Bootstrapping an empirical Bayes estimator of the distribution of historical controls in carcinogen bioassay

DOI10.1016/0378-3758(94)00021-MzbMath0812.62101MaRDI QIDQ1345566

Mieczyslaw Szyszkowicz, Robert T. Smythe, Daniel Krewski, Anup Dewanji

Publication date: 26 April 1995

Published in: Journal of Statistical Planning and Inference (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/0378-3758(94)00021-m

zbMATH Keywords

bioassay; bootstrap variance estimator; carcinogenicity; tests for trend; discrete uniform distribution; discrete empirical Bayes shrinkage estimator; generalized score tests; historical control tumor response probabilities; logistic dose response model; tumor occurrence rates

Mathematics Subject Classification ID

62P10: Applications of statistics to biology and medical sciences; meta analysis

62G09: Nonparametric statistical resampling methods

62C12: Empirical decision procedures; empirical Bayes procedures

Cites Work

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• The use of historical control information in modelling dose response relationships in carcinogenesis
• Combining Historical and Randomized Controls for Assessing Trends in Proportions
• Incorporating Historical Controls in Testing for a Trend in Proportions
• Algorithm AS 221: Maximum Likelihood Estimation of a Mixing Distribution
• Empirical Bayes Confidence Intervals Based on Bootstrap Samples
• Nonparametric Maximum Likelihood Estimation of a Mixing Distribution
• Stein's Estimation Rule and Its Competitors--An Empirical Bayes Approach