Dynamics of cellular homeostasis: Recovery time for a perturbation from equilibrium

DOI10.1007/BF02459460MaRDI QIDQ1363030zbMATH OpenOpenAlexFDO

Authors Alan M. Weinstein

Publication date 22 August 1999

Published in Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/bf02459460

zbMATH Keywords

homeostasision channels

Mathematics Subject Classification ID

Neural biology (92C20) Physiology (general) (92C30)

Review text

The author develops a mathematical model of the principal cell of the rat cortical collecting duct, in which ion channel permeabilities are either constant or regulated. It is found that the latter version exhibits enhanced cellular homeostasis while the difference in recovery time between the two versions is small. An approximate analysis is carried out by casting the model into a dynamical system with constant coefficients.

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Cites work

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• Erratum to: ``Mathematical properties of pump-leak models of cell volume control and electrolyte balance
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