More powerful logrank permutation tests for two-sample survival data

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Publication:148347

DOI10.48550/ARXIV.1807.05504arXiv1807.05504MaRDI QIDQ148347FDOQ148347


Authors: Marc Ditzhaus, Sarah Friedrich Edit this on Wikidata


Publication date: 15 July 2018

Abstract: Weighted logrank tests are a popular tool for analyzing right censored survival data from two independent samples. Each of these tests is optimal against a certain hazard alternative, for example the classical logrank test for proportional hazards. But which weight function should be used in practical applications? We address this question by a flexible combination idea leading to a testing procedure with broader power. Beside the test's asymptotic exactness and consistency its power behaviour under local alternatives is derived. All theoretical properties can be transferred to a permutation version of the test, which is even finitely exact under exchangeability and showed a better finite sample performance in our simulation study. The procedure is illustrated in a real data example.








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