Optimum designs for estimating ED_p based on raw optical density data

DOI10.1016/S0378-3758(01)00120-3MaRDI QIDQ1600749zbMATH OpenFDO

Authors A. S. Hedayat, Bo Yan, John M. Pezzuto

Publication date 16 June 2002

Published in Journal of Statistical Planning and Inference (Search for Journal in Brave)

zbMATH Keywords

robustnessinformation matrixnonlinear modelefficient designsdrug discoverydose-response analysisskewed models

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Optimal statistical designs (62K05)

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Cites work

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• An extension of the General Equivalence Theorem to nonlinear models
• Experimental Design for Binary Data
• Modeling and Identifying Optimum Designs for Fitting Dose-Response Curves Based on Raw Optical Density Data
• On D-optimal designs for binary data
• Optimality Assessment in the Enzyme-Linked Immunosorbent Assay (ELISA)
• Optimum Allocation in Linear Regression Theory
• Selection of Dose Levels for Estimating a Percentage Point of a Logistic Quantal Response Curve

Cited in

(3)

• Optimal and efficient designs for 2-parameter nonlinear models
• Locally D-optimal designs based on a class of composed models resulted from blending Emax and one-compartment models
• Support points of locally optimal designs for nonlinear models with two parameters

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Uses Software

• ELISA

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