Biomarker assessment and combination with differential covariate effects and an unknown gold standard, with an application to Alzheimer's disease

DOI10.1214/17-AOAS1085zbMATH Open1405.62213OpenAlexW2883870106MaRDI QIDQ1624842FDOQ1624842

Authors: Zheyu Wang, Xiao-Hua Zhou 

Publication date: 16 November 2018

Published in: The Annals of Applied Statistics (Search for Journal in Brave)

Full work available at URL: https://projecteuclid.org/euclid.aoas/1532743491

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zbMATH Keywords

identifiabilityfinite mixture modelsdiagnostic accuracyAlzheimer's diseaselatent profile modeldifferential covariate effect

Mathematics Subject Classification ID

Classification and discrimination; cluster analysis (statistical aspects) (62H30) Applications of statistics to biology and medical sciences; meta analysis (62P10)

Cites Work

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Cited In (3)

• Extending Hui-Walter framework to correlated outcomes with application to diagnosis tests of an eye disease among premature infants
• Model-based clustering for assessing the prognostic value of imaging biomarkers and mixed type tests
• Data-driven biomarker analysis using computational omics approaches to assess neurodegenerative disease progression

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