P2X\(_7\) regenerative-loop potentiation of glutamate synaptic transmission by microglia and astrocytes

DOI10.1016/J.JTBI.2009.07.024zbMath1403.92040OpenAlexW2063771518WikidataQ45915858 ScholiaQ45915858MaRDI QIDQ1628800

Les Farnell, William G. Gibson, Max R. Bennett

Publication date: 11 December 2018

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2009.07.024

zbMATH Keywords

microgliaATPastrocytesglutamateP2X\(_7\)

Mathematics Subject Classification ID

Neural biology (92C20) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Biochemistry, molecular biology (92C40) Cell biology (92C37)

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Cites Work

• Origins of blood volume change due to glutamatergic synaptic activity at astrocytes abutting on arteriolar smooth muscle cells
• Short term synaptic depression model -- analytical solution and analysis
• Metabotropic receptor activation, desensitization and sequestration. I: Modelling calcium and inositol 1,4,5-trisphosphate dynamics following receptor activation
• A mathematical model of ion movements in grey matter during a stroke
• Mechanisms of calcium sequestration during facilitation at active zones of an amphibian neuromuscular junction

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