A trade-off between neutrality and adaptability limits the optimization of viral quasispecies

DOI10.1016/J.JTBI.2009.07.034zbMATH Open1403.92163OpenAlexW2043393264WikidataQ43923149 ScholiaQ43923149MaRDI QIDQ1628840FDOQ1628840

Authors: Jacobo Aguirre, Ester Lázaro, S. C. Manrubia 

Publication date: 11 December 2018

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2009.07.034

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zbMATH Keywords

growth ratemutation-selection equilibriumfitnessbottleneckrecovery timegenetic robustnessout-of-equilibrium competition

Mathematics Subject Classification ID

Genetics and epigenetics (92D10) Problems related to evolution (92D15)

Cites Work

• Stationary mutant distributions and evolutionary optimization
• Adaptive evolution on neutral networks

Cited In (3)

• A quasispecies on a moving oasis
• Redundancy-selection trade-off in phenotype-structured populations
• Virus replication as a phenotypic version of polynucleotide evolution

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