A trade-off between neutrality and adaptability limits the optimization of viral quasispecies

DOI10.1016/J.JTBI.2009.07.034MaRDI QIDQ1628840zbMATH OpenOpenAlexWikidataFDO

Authors Jacobo Aguirre, Ester Lázaro, S. C. Manrubia

Publication date 11 December 2018

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.jtbi.2009.07.034

zbMATH Keywords

bottleneckfitnessgenetic robustnessgrowth ratemutation-selection equilibriumout-of-equilibrium competitionrecovery time

Mathematics Subject Classification ID

Genetics and epigenetics (92D10) Problems related to evolution (92D15)

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Cites work

• Adaptive evolution on neutral networks
• Stationary mutant distributions and evolutionary optimization

Cited in

(3)

• Redundancy-selection trade-off in phenotype-structured populations
• A quasispecies on a moving oasis
• Virus replication as a phenotypic version of polynucleotide evolution

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