A new method for evaluation of the Fisher information matrix for discrete mixed effect models using Monte Carlo sampling and adaptive Gaussian quadrature

DOI10.1016/j.csda.2016.10.011zbMath1464.62173MaRDI QIDQ1654246

Sebastian Ueckert, France Mentré

Publication date: 7 August 2018

Published in: Computational Statistics and Data Analysis (Search for Journal in Brave)

Full work available at URL: https://www.hal.inserm.fr/inserm-01397584/file/manuscriptCSDA_Ueckert.pdf

zbMATH Keywords

Fisher information matrix; discrete data; optimal design; generalized linear mixed model; nonlinear mixed effect models

Mathematics Subject Classification ID

62-08: Computational methods for problems pertaining to statistics

62K05: Optimal statistical designs

62J12: Generalized linear models (logistic models)

Related Items

Optimal designs for discrete-time survival models with random effects

Uses Software

• R
• Statmod
• PopED

Cites Work

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