On a nonlinear model for tumor growth in a cellular medium
Dependence of solutions to PDEs on initial and/or boundary data and/or on parameters of PDEs (35B30) Navier-Stokes equations (35Q30) PDEs in connection with biology, chemistry and other natural sciences (35Q92) Sobolev spaces and other spaces of ``smooth functions, embedding theorems, trace theorems (46E35) Existence, uniqueness, and regularity theory for compressible fluids and gas dynamics (76N10) Flows in porous media; filtration; seepage (76S05) Cell biology (92C37)
This article is concerned with an analytical study of a nonlinear model for tumor growth within a cellular medium. The governing system is given by a multi-phase flow of cancer cells. The evolution of tumor growth occurs in the presence of proliferating and quiescent cells as well as waste and a nutrient. The tumor is modeled as a growing, time-dependent domain \(\Omega\) with boundary \(\partial\Omega\). The total density of cancerous cells is allowed to vary. The authors obtain global-in-time weak solutions for this tumor growth model. They explain that their approach makes use of ``penalization of the boundary behavior, diffusion, viscosity and pressure in the weak formulation as well as convergence and compactness arguments (...).
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