Semiparametric covariate-modulated local false discovery rate for genome-wide association studies

DOI10.1214/17-AOAS1077zbMATH Open1383.62301OpenAlexW2949572358MaRDI QIDQ1697396FDOQ1697396

Authors: Rong W. Zablocki, Richard A. Levine, Andrew J. Schork, Shujing Xu, Chun C. Fan, Wesley K. Thompson, Yunpeng Wang 

Publication date: 19 February 2018

Published in: The Annals of Applied Statistics (Search for Journal in Brave)

Full work available at URL: https://projecteuclid.org/euclid.aoas/1514430285

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zbMATH Keywords

Bayesian mixture modelgenome-wide association studymixture of expertsB-spline densitiesmultiple-comparison procedures

Mathematics Subject Classification ID

Bayesian inference (62F15) Applications of statistics to biology and medical sciences; meta analysis (62P10) Protein sequences, DNA sequences (92D20) Paired and multiple comparisons; multiple testing (62J15)

Cited In (8)

• Covariate Adaptive False Discovery Rate Control With Applications to Omics-Wide Multiple Testing
• Minimax powerful functional analysis of covariance tests with application to longitudinal genome‐wide association studies
• Efficient testing and effect size estimation for set‐based genetic association inference via semiparametric multilevel mixture modeling
• Covariate adaptive familywise error rate control for genome-wide association studies
• A semi-parametric Bayesian model for semi-continuous longitudinal data
• Covariate-modulated large-scale multiple testing under dependence
• Covariate-adjusted multiple testing in genome-wide association studies via factorial hidden Markov models
• Covariate-adjusted precision matrix estimation with an application in genetical genomics

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