Bootstrap testing for cross-correlation under low firing activity

DOI10.1007/S10827-015-0557-5MaRDI QIDQ1704891zbMATH OpenOpenAlexWikidataFDO

Authors Ricardo Cao, Nelson Espinosa, Javier Cudeiro, Jorge Mariño, Aldana M. González Montoro

Publication date 13 March 2018

Published in Journal of Computational Neuroscience (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/1412.5004

zbMATH Keywords

hypothesis testingsynchronizationsleep-wakespontaneous activitytonic activity

Mathematics Subject Classification ID

Bootstrap, jackknife and other resampling methods (62F40) Applications of statistics to biology and medical sciences; meta analysis (62P10) General biostatistics (92B15) Neural biology (92C20)

Abstract: A new cross-correlation synchrony index for neural activity is proposed. The index is based on the integration of the kernel estimation of the cross-correlation function. It is used to test for the dynamic synchronization levels of spontaneous neural activity under two induced brain states: sleep-like and awake-like. Two bootstrap resampling plans are proposed to approximate the distribution of the test statistics. The results of the first bootstrap method indicate that it is useful to discern significant differences in the synchronization dynamics of brain states characterized by a neural activity with low firing rate. The second bootstrap method is useful to unveil subtle differences in the synchronization levels of the awake-like state, depending on the activation pathway.

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Cites work

• scientific article; zbMATH DE number 3222478 (Why is no real title available?)
• A Flexible Method to Measure Synchrony in Neuronal Firing
• Cross nearest-spike interval based method to measure synchrony dynamics
• Dynamic linear response of the SK spin glass coupled microscopically to a bath
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• The Stationary Bootstrap
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Cited in

(1)

• Significant FMRI Neurologic Synchrony Using Monte Carlo Methods

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