Hybrid reductions of computational models of ion channels coupled to cellular biochemistry

DOI10.1007/978-3-319-45177-0_17zbMATH Open1382.92009OpenAlexW2509528172MaRDI QIDQ1706595FDOQ1706595

Authors: Jasha Sommer-Simpson, John Reinitz, Leonid Fridlyand, Louis Philipson, Ovidiu Radulescu 

Publication date: 22 March 2018

Full work available at URL: https://doi.org/10.1007/978-3-319-45177-0_17

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zbMATH Keywords

ion channelspancreatic beta-cellshybrid reductions

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Computational methods for problems pertaining to biology (92-08)

Cited In (4)

• Exact reductions of Markovian dynamics for ion channels with a single permissive state
• Algorithmic reduction of biological networks with multiple time scales
• Compositionality results for cardiac cell dynamics
• Model-order reduction of ion channel dynamics using approximate bisimulation

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