A phase I dose-finding study based on polychotomous toxicity responses

DOI10.4310/SII.2012.v5.n4.a8zbMath1386.62069OpenAlexW2312751837MaRDI QIDQ1708945

Keying Ye, Xiao-Bin Yang

Publication date: 27 March 2018

Published in: Statistics and Its Interface (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.4310/sii.2012.v5.n4.a8

zbMATH Keywords

Markov chain Monte Carlo (MCMC)latent variablephase I clinical trialcontinual reassessment method (CRM)cumulative probit model

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Bayesian inference (62F15) Sequential statistical design (62L05)

Related Items (2)

A system for determining maximum tolerated dose in clinical trial ⋮ A study of the probit model with latent variables in Phase I clinical trials

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