Receptor heterogeneity in optical biosensors

DOI10.1007/S00285-017-1158-XzbMath1392.92030OpenAlexW2735311426WikidataQ47766816 ScholiaQ47766816MaRDI QIDQ1709393

Ryan M. Evans, David A. Edwards

Publication date: 5 April 2018

Published in: Journal of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s00285-017-1158-x

zbMATH Keywords

numerical methodsasymptotic analysispartial differential equationskinetic rate constantsoptical biosensorsbiochemistry

Mathematics Subject Classification ID

PDEs in connection with biology, chemistry and other natural sciences (35Q92) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Asymptotic approximations, asymptotic expansions (steepest descent, etc.) (41A60) Numerical differentiation (65D25) Numerical integration (65D30)

Cites Work

• Convection effects in the BIAcore dextran layer: surface reaction model
• Multiple surface reactions in arrays with applications to optical biosensors
• Transport effects on surface reaction arrays: biosensor applications
• The effect of a receptor layer on the measurement of rate constants
• Testing the validity of the effective rate constant approximation for surface reaction with transport
• Transport effects on multiple-component reactions in optical biosensors
• Refining the measurement of rate constants in the BIAcore
• Transport effects on surface-volume biological reactions
• Convection Effects in Thin Reaction Zones: Applications to Biacore
• Estimating rate constants in a convection-diffusion system with a boundary reaction

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