Mathematical model and computer simulations of telomere loss

DOI10.1016/j.jtbi.2019.01.007zbMath1406.92399OpenAlexW2909323045WikidataQ91003162 ScholiaQ91003162MaRDI QIDQ1721796

Ivica Rubelj, Miljenko Huzak, Ana Martinčić Špoljarić

Publication date: 13 February 2019

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2019.01.007

zbMATH Keywords

abrupt shorteninghuman fibroblastsincomplete replicationreplicative senescencestochastic cell ageing dynamics

Mathematics Subject Classification ID

Cell biology (92C37) Genetics and epigenetics (92D10)

Cites Work

• Stochastic models of telomere shortening
• Modeling growth and telomere dynamics in \textit{Saccharomyces cerevisiae}
• Stochastic modeling of length-dependent telomere shortening in \textit{Corvus monedula}
• A mathematical model of cellular apoptosis and senescence through the dynamics of telomere loss
• A branching process model of telomere shortening

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