Modeling the effects of variable feeding patterns of larval ticks on the transmission of \textit{Borrelia lusitaniae} and \textit{Borrelia afzelii}

DOI10.1016/J.TPB.2017.06.004MaRDI QIDQ1746091zbMATH OpenOpenAlexWikidataFDO

Authors Luca Ferreri, Silvia Perazzo, E. Venturino, Mario Giacobini, Luigi Bertolotti, Alessandro Mannelli

Publication date 24 April 2018

Published in Theoretical Population Biology (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/1707.02463

zbMATH Keywords

Borrelia afzeliiBorrelia lusitaniaelizardLyme diseasemathematical modelrodent

Mathematics Subject Classification ID

Stability of solutions to ordinary differential equations (34D20) Epidemiology (92D30)

Abstract: Spirochetes belonging to the Borrelia burgdoferi sensu lato (sl) group cause Lyme Borreliosis (LB), which is the most commonly reported vector-borne zoonosis in Europe. B. burgdorferi sl is maintained in nature in a complex cycle involving Ixodes ricinus ticks and several species of vertebrate hosts. The transmission dynamics of B. burgdorferi sl is complicated by the varying competence of animals for different genospecies of spirochetes that, in turn, vary in their capability of causing disease. In this study, a set of difference equations simplifying the complex interaction between vectors and their hosts (competent and not for Borrelia) is built to gain insights into conditions underlying the dominance of B. lusitaniae (transmitted by lizards to susceptible ticks) and the maintenance of B. afzelii (transmitted by wild rodents) observed in a study area in Tuscany, Italy. Findings, in agreement with field observations, highlight the existence of a threshold for the fraction of larvae feeding on rodents below which the persistence of B. afzelii is not possible. Furthermore, thresholds change as nonlinear functions of the expected number of nymph bites on mice, and the transmission and recovery probabilities. In conclusion, our model provided an insight into mechanisms underlying the relative frequency of different Borrelia genospecies, as observed in field studies.

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Cites work

• Effects of tick population dynamics and host densities on the persistence of tick-borne infections
• Thresholds for disease persistence in models for tick-borne infections including non-viraemic transmission, extended feeding and tick aggregation

Cited in

(15)

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• The role of non-viraemic transmission on the persistence and dynamics of a tick borne virus-louping ill in red grouse (\textit{Lagopus lagopus scoticus}) and mountain hares (\textit{Lepus timidus})
• Editorial. Mathematical epidemiology for a later age
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• Identifying requirements for the invasion of a tick species and tick-borne pathogen through TICKSIM
• Estimation of the Transmission Probability of Lyme Borreliosis
• Range expansion of \textit{Ixodes scapularis} ticks and of \textit{Borrelia burgdorferi} by migratory birds
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• Ticks and tick-borne diseases: a vector-host interaction model for the brown ear tick (Rhipicephalus appendiculatus)
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