Variance in estimated pairwise genetic distance under high versus low coverage sequencing: the contribution of linkage disequilibrium

DOI10.1101/108928MaRDI QIDQ1746104zbMATH OpenOpenAlexWikidataFDO

Authors M. Shpak, Yang Ni, Jie Lü, P. Müller

Publication date 24 April 2018

Published in Theoretical Population Biology (Search for Journal in Brave)

Copyright license Creative Commons Attribution 4.0 International

Full work available at URL https://doi.org/10.1101/108928

zbMATH Keywords

coveragelinkage disequilibriumnext-generation sequencingcancer genomicsgenetic distancepooled sampling

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Analysis of variance and covariance (ANOVA) (62J10) Genetics and epigenetics (92D10) Problems related to evolution (92D15)

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Cites work

• On the number of segregating sites in genetical models without recombination
• Statistical properties of segregating sites

Cited in

(2)

• The variance of pairwise nucleotide differences in two populations with migration
• On the optimal design of genetic variant discovery studies

Describes a project that uses

Uses Software

• GATK
• BWA

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