On the probability of random genetic mutations for various types of tumor growth

DOI10.1007/S11538-012-9717-1MaRDI QIDQ1758071zbMATH OpenOpenAlexWikidataFDO

Authors Cristian Tomasetti

Publication date 7 November 2012

Published in Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL http://europepmc.org/articles/pmc3843941

zbMATH Keywords

ordinary differential equationsbranching processesdrug resistancestem cells

Mathematics Subject Classification ID

Medical applications (general) (92C50) Dynamical systems in biology (37N25) Applications of branching processes (60J85) Cell biology (92C37)

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Cites work

• scientific article; zbMATH DE number 1114142 (Why is no real title available?)
• A mathematical model of cycle-specific chemotherapy
• A model for the resistance of tumor cells to cancer chemotherapeutic agents
• A stochastic model for the origin and treatment of tumors containing drug-resistant cells
• An elementary approach to modeling drug resistance in cancer
• ON THE FOUNDATIONS OF CANCER MODELLING: SELECTED TOPICS, SPECULATIONS, AND PERSPECTIVES
• Progress of a half century in the study of the Luria-Delbrück distribution
• The dynamics of gene amplification described as a multitype compartmental model and as a branching process
• The mathematical modelling of adjuvant chemotherapy scheduling: incorporating the effects of protocol rest phases and pharmacokinetics

Cited in

(7)

• Evolutionary dynamics of tumor progression with random fitness values
• Estimation of spontaneous mutation rates
• A decomposable branching process in a Markovian environment
• Accumulation of neutral mutations in growing cell colonies with competition
• Universal asymptotic clone size distribution for general population growth
• Cellular replication limits in the Luria-Delbrück mutation model
• Stochastic Modelling of Multiple Random Genetic Mutations Under the Cancer Stem Cell Hypothesis

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