The computation of biomarkers in pharmacokinetics with the aid of singular perturbation methods

DOI10.1007/S00285-018-1257-3MaRDI QIDQ1789076zbMATH OpenOpenAlexWikidataFDO

Authors Jie Ma, James P. Keener

Publication date 9 October 2018

Published in Journal of Mathematical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/s00285-018-1257-3

zbMATH Keywords

biomarkerscompartment modelscomposite expansionsmethod of matched asymptotic expansionssingular perturbation methods

Mathematics Subject Classification ID

Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)

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Cites work

• scientific article; zbMATH DE number 193117 (Why is no real title available?)
• Mathematical physiology
• On the Lambert \(w\) function

Cited in

(2)

• Critical dependence of blood-borne biomarker concentrations on the half-lives of their carrier proteins
• Mathematical solution of a pharmacokinetic model with simultaneous first-order and Hill-type elimination

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