The origin of the genetic code in the ocean abysses: new comparisons confirm old observations

DOI10.1016/J.JTBI.2013.05.019zbMATH Open1397.92453OpenAlexW2036760950WikidataQ44143328 ScholiaQ44143328MaRDI QIDQ1790777FDOQ1790777

Authors: Massimo Di Giulio 

Publication date: 4 October 2018

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2013.05.019

Recommendations

• A methanogen hosted the origin of the genetic code
• The genetic code is not an optimal code in a model taking into account both the biosynthetic relationships between amino acids and their physicochemical properties
• The evolution of the genetic code took place in an anaerobic environment
• Structuring of the genetic code took place at acidic pH
• Evolution of the genetic code based on conservative changes of codons, amino acids, and aminoacyl tRNA synthetases

zbMATH Keywords

GC contentbarophilic organismsgenetic code codon numberpolarity and molecular weight of amino acidsprimordial physical environment

Mathematics Subject Classification ID

Genetics and epigenetics (92D10) Ecology (92D40)

Cites Work

• A methanogen hosted the origin of the genetic code
• The universal ancestor was a thermophile or a hyperthermophile: tests and further evidence
• Structuring of the genetic code took place at acidic pH
• The evolution of the genetic code took place in an anaerobic environment
• Title not available (Why is that?)

Cited In (2)

• Metabolic Constraints on the Evolution of Genetic Codes: Did Multiple Preaerobic’ Ecosystem Transitions Entrain Richer Dialects via Serial Endosymbiosis?
• The evolution of the genetic code took place in an anaerobic environment

Uses Software

• PSI-BLAST
• BLAST

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