Equilibrium binding of multivalent ligands to cells: Effects of cell and receptor density
DOI10.1016/0025-5564(96)00022-3zbMATH Open0856.92006OpenAlexW1991278456WikidataQ52301341 ScholiaQ52301341MaRDI QIDQ1817441FDOQ1817441
Bernhard Sulzer, Alan S. Perelson
Publication date: 24 February 1997
Published in: Mathematical Biosciences (Search for Journal in Brave)
Full work available at URL: https://doi.org/10.1016/0025-5564(96)00022-3
B cellscell densityligand bindingaviditymultivalent ligandscell surface receptorsequilibrium binding propertieshaptenated polymersimmunon theory of B-cell activationligand depletionligand-induced cell proliferationreceptor concentration
Biochemistry, molecular biology (92C40) Physiology (general) (92C30) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Asymptotic theory for ordinary differential equations (34E99)
Cites Work
- Title not available (Why is that?)
- The kientics of bivalent ligand-bivalent receptor aggregation: Ring formation and the breakdown of the equivalent site approximation
- Receptor clustering on a cell surface. I. Theory of receptor cross- linking by ligands bearing two chemically identical functional groups
- Receptor clustering on a cell surface. III. Theory of receptor cross- linking by multivalent ligands: Description by ligand states
- Interpretation of Scatchard plots for aggregating receptor systems
Cited In (6)
- Scaffold-mediated nucleation of protein signaling complexes: elementary principles
- Chemoreception by a cell with age-dependent receptor binding sites
- Impact of plasma-protein binding on receptor occupancy: an analytical description
- Monotonicity of interleukin-1 receptor-ligand binding with respect to antagonist in the presence of decoy receptor
- Equilibrium competition binding assay: inhibition mechanism from a single dose response
- A model of cell surface receptor aggregation
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